TNM staging according with the 8th edition
​T – Primary Tumour
TX – Primary tumour cannot be assessed
T0 – No evidence of primary tumour
Urethra (male and female)
Ta – Non-invasive papillary, polypoid, or verrucous carcinoma
Tis – Carcinoma in situ
T1 – Tumour invades subepithelial connective tissue
T2 – Tumour invades any of the following: corpus spongiosum, prostate, periurethral muscle
T3 –Tumour invades any of the following: corpus cavernosum, beyond prostatic capsule, anterior vagina, bladder neck (extraprostatic extension)
T4 – Tumour invades other adjacent organs (invasion of the bladder)
Urothelial (transitional cell) carcinoma of the prostate
Tispu – Carcinoma in situ, involvement of prostatic urethra
Tispd – Carcinoma in situ, involvement of prostatic ducts
T1 – Tumour invades subepithelial connective tissue (for tumours involving prostatic urethra only)
T2 – Tumour invades any of the following: prostatic stroma, corpus sponsiosum, periurethral muscle
T3 – Tumour invades any of the following: corpus cavernosum, beyond prostatic capsule, bladder neck (extraprostatic extension)
T4 – Tumour invades other adjacent organs (invasion of the bladder or rectum)
N - Regional Lymph Nodes
NX – Regional lymph nodes cannot be assessed
N0 – No regional lymph node metastasis
N1 – Metastasis in a single lymph node
N2 – Metastasis in multiple lymph nodes
M - Distant Metastasis
M0 – No distant metastasis
M1 – Distant metastasis
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Grade of tumor
Urothelial urethral carcinoma
PUNLMP – Papillary urothelial neoplasm of low malignant potential
Low grade – Well differentiated
High grade – Poorly differentiated
Non-urothelial urethral carcinoma
Gx – Tumour grade not assessable
G1 – Well differentiated
G2 – Moderately differentiated
G3 – Poorly differentiated
